Articles / Today's Best Bets & Model Picks — September 22, 2026
Sep 22, 2026
Today's Best Bets & Model Picks — September 22, 2026
How this was made: generated automatically from the picks, odds and final scores in our database. A language model writes the opening paragraph from those numbers; the numbers are never edited by hand.
Today, 84 games will take place across four major leagues, including Esports, MLB, NHL, and Tennis, with the latter two featuring a total of 30 matchups. Meanwhile, a live model pick selection will be available on our platform, comprising 19 picks that have a combined confidence level of 57%. The stakes are high, and our analytical models are ready to provide insights and recommendations for bettors looking to capitalize on the diverse range of contests on the 2026-09-22 slate.
Which picks did the models make today?
| League | Matchup | Pick | Confidence |
|---|---|---|---|
| MLB | Tampa Bay Rays @ New York Yankees | Spread — Home -1.5 | 75 |
| MLB | Miami Marlins @ Chicago Cubs | Spread — Away +1.5 | 66 |
| MLB | Cleveland Guardians @ Boston Red Sox | Moneyline — Home | 59 |
| MLB | Milwaukee Brewers @ Philadelphia Phillies | Moneyline — Home | 58 |
| MLB | Tampa Bay Rays @ New York Yankees | Spread — Home -1.5 | 58 |
| MLB | Cleveland Guardians @ Boston Red Sox | Spread — Home -1.5 | 56 |
| MLB | Cleveland Guardians @ Boston Red Sox | Moneyline — Home | 55 |
| MLB | Tampa Bay Rays @ New York Yankees | Moneyline — Home | 55 |
| MLB | Washington Nationals @ Detroit Tigers | Moneyline — Home | 55 |
| MLB | Milwaukee Brewers @ Philadelphia Phillies | Moneyline — Home | 55 |
| MLB | St Louis Cardinals @ Pittsburgh Pirates | Moneyline — Home | 55 |
| MLB | Toronto Blue Jays @ Baltimore Orioles | Moneyline — Home | 55 |
| MLB | Cincinnati Reds @ Atlanta Braves | Moneyline — Home | 55 |
| MLB | Chicago White Sox @ Kansas City Royals | Moneyline — Away | 55 |
| MLB | Miami Marlins @ Chicago Cubs | Moneyline — Away | 55 |
| MLB | Tampa Bay Rays @ New York Yankees | Spread — Home -1.5 | 55 |
| MLB | Tampa Bay Rays @ New York Yankees | Spread — Home -1.5 | 53 |
| MLB | Tampa Bay Rays @ New York Yankees | Spread — Home -1.5 | 53 |
| MLB | Tampa Bay Rays @ New York Yankees | Moneyline — Home | 52 |
What else is on today's slate?
MLB
| Start (UTC) | Matchup | Our pick |
|---|---|---|
| 5:05 PM | Tampa Bay Rays @ New York Yankees | Spread — Home -1.5 · Moneyline — Home |
| 10:35 PM | Toronto Blue Jays @ Baltimore Orioles | Moneyline — Home |
| 10:40 PM | Washington Nationals @ Detroit Tigers | Moneyline — Home |
| 10:40 PM | St Louis Cardinals @ Pittsburgh Pirates | Moneyline — Home |
| 10:40 PM | Milwaukee Brewers @ Philadelphia Phillies | Moneyline — Home · Moneyline — Home |
| 10:45 PM | Cleveland Guardians @ Boston Red Sox | Moneyline — Home · Spread — Home -1.5 · Moneyline — Home |
| 11:05 PM | Tampa Bay Rays @ New York Yankees | Spread — Home -1.5 · Spread — Home -1.5 · Moneyline — Home · Spread — Home -1.5 · Spread — Home -1.5 |
| 11:15 PM | Cincinnati Reds @ Atlanta Braves | Moneyline — Home |
| 11:40 PM | Miami Marlins @ Chicago Cubs | Spread — Away +1.5 · Moneyline — Away |
| 11:40 PM | Chicago White Sox @ Kansas City Royals | Moneyline — Away |
NHL
| Start (UTC) | Matchup | Our pick |
|---|---|---|
| 11:00 PM | New York Islanders @ New York Rangers | — |
| 11:00 PM | Philadelphia Flyers @ Boston Bruins | — |
| 11:00 PM | Florida Panthers @ Carolina Hurricanes | — |
| 11:00 PM | Edmonton Oilers @ Winnipeg Jets | — |
| 11:00 PM | Columbus Blue Jackets @ Buffalo Sabres | — |
| 11:00 PM | Detroit Red Wings @ Pittsburgh Penguins | — |
WNBA
| Start (UTC) | Matchup | Our pick |
|---|---|---|
| 11:30 PM | Connecticut Sun @ Washington Mystics | — |
UFC
| Start (UTC) | Matchup | Our pick |
|---|---|---|
| 11:00 PM | Emilio Quissua vs Damian Piwowarczyk | — |
| 11:00 PM | Alvi Dasuyev vs Jaden Ortega | — |
| 11:00 PM | Theo Haig vs Norbert Novenyi Jr | — |
| 11:00 PM | Marcos Degli vs Paris Moran | — |
| 11:00 PM | Piero Guaylupo vs Callum Connor | — |
Tennis
| Start (UTC) | Matchup | Our pick |
|---|---|---|
| 1:00 AM | Sofia Kenin vs Alina Charaeva | — |
| 2:00 AM | Linda Fruhvirtova vs Maria Sakkari | — |
| 7:00 AM | Ivan Ivanov vs Filip Jianu | — |
| 7:00 AM | Alexander Vasilev vs Felix Gill | — |
| 7:00 AM | Joel Schwaerzler vs Maxime Chazal | — |
| 8:00 AM | Marvin Moeller vs Stefano Travaglia | — |
| 8:00 AM | Thiago Monteiro vs Mika Petkovic | — |
| 8:00 AM | Marta Lombardini vs Aurora Zantedeschi | — |
| 8:00 AM | Billy Harris vs Nicolai Budkov Kjaer | — |
| 8:00 AM | Laura Pigossi vs Ekaterine Gorgodze | — |
| 8:00 AM | Nikolas Sanchez Izquierdo vs Lukas Neumayer | — |
| 8:00 AM | Alicia Herrero Linana vs Barbora Palicova | — |
| 8:00 AM | Jesper De Jong vs Remy Bertola | — |
| 8:00 AM | Julia Grabher vs Jennifer Ruggeri | — |
| 8:00 AM | Kimmer Coppejans vs Sean Cuenin | — |
| 8:00 AM | Daniel Rincon vs Dino Prizmic | — |
| 8:00 AM | Samira De Stefano vs Julie Struplova | — |
| 8:00 AM | Gianluca Cadenasso vs Matthew William Donald | — |
| 8:00 AM | Edas Butvilas vs Grigor Dimitrov | — |
| 8:00 AM | Maria Lourdes Carle vs Nuria Brancaccio | — |
| 10:00 AM | Elena Malygina vs Mina Hodzic | — |
| 10:00 AM | Katie Swan vs Erika Andreeva | — |
| 11:30 AM | Gabriela Knutson vs Katherine Sebov | — |
| 12:00 PM | Celia Cervino Ruiz vs Matilde Jorge | — |
| 1:00 PM | Renzo Olivo vs Facundo Mena | — |
| 1:00 PM | Carol Young Suh Lee vs Harmony Tan | — |
| 1:00 PM | Hugo Dellien vs Matheus Pucinelli De Almeida | — |
| 1:30 PM | Mia Pohankova vs Francisca Jorge | — |
| 2:30 PM | Franco Roncadelli vs Gonzalo Bueno | — |
| 2:30 PM | Hernan Casanova vs Murkel Dellien | — |
+ 6 more Tennis games today.
Esports
| Start (UTC) | Matchup | Our pick |
|---|---|---|
| 7:00 AM | Gamerlegion vs Team Nemesis | — |
| 9:00 AM | Team Lynx vs Zero Tenacity | — |
| 10:00 AM | Team Cobra vs Pipsqueak 4 | — |
| 10:00 AM | 1win vs Natus Vincere | — |
| 10:00 AM | Bilibili Gaming Junior vs Kt Rolster Challengers | — |
| 11:00 AM | Ctbc Flying Oyster Academy vs Movistar Koi Fenix | — |
| 12:00 PM | Gpk Team vs Soloteam | — |
| 12:00 PM | T1 Academy vs Edward Gaming Youth Team | — |
| 12:00 PM | Nemiga Gaming vs Spirit Academy | — |
| 1:00 PM | Dn Soopers Challengers vs Fuego | — |
| 1:00 PM | Aurora vs Lgd Gaming | — |
| 1:00 PM | Hokori vs Mouz | — |
| 1:00 PM | Daxak Team vs Avice Team | — |
| 3:00 PM | Gamespace Mediterranean College Esports vs Barca Esports | — |
| 3:00 PM | Yellow Submarine vs Two Move | — |
| 3:00 PM | Cita Kaizen vs Unicorns Of Love Sexy Edition | — |
| 3:00 PM | Ucam Esports Club vs Su Esports | — |
| 3:00 PM | Lodis vs Skillcamp Esport | — |
| 3:00 PM | Ns Team vs Travoman Team | — |
| 6:00 PM | Pyramid Iv Esports vs Arctic Pandas | — |
| 6:00 PM | Bubliki vs Otf | — |
| 6:00 PM | Kalmychata vs Team Synapse | — |
| 6:00 PM | Stray Team vs Ybn Team | — |
| 6:00 PM | Mcon Esports vs Verdant | — |
| 6:00 PM | Team Aqua Asd vs The Otter Side | — |
| 6:00 PM | Tf vs Bubliki | — |
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